Statistical data analysis was performed with SPSS 26.0 for Windows (SPSS Inc., Chicago, IL). The Shapiro-Wilk Test was used to test the normality. The numeric variables were presented as total numbers (n) and mean ± standard deviation values, whereas number (n) and frequencies (%) were used to present categorical variables. Abnormally distributed data were represented by median and 5th - 95th percentiles range. A two-way mixed effect model based on a single rating assessed the intra-rater repeatability of the sphenoid sinus volume. Mean estimations and 95% confidence intervals (CI) were reported for each intraclass correlation coefficient (ICC). The association of the PNS development between gender and three race cohorts was performed using the Mann-Whitney U test and Kruskal Wallis test, respectively, and the corresponding p values were obtained. The p - value was considered significant when < 0.05. The correlation between sinus volume and age was assessed using Spearman's rank coefficient.
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