2-phenylsulphonyloxy-3a,4,7,7a-tetrahydroisoindol-1,3-dione
(8 ) (0.5 g, 1 mmol) was refluxed with cyclohexylamine,
butylamine, benzylamine, p-aminoacetophenone, p-aminoethylbenzoate (0.1 g, 2 mmol) in glacial acetic acid
or dry toluene for 3 h. After cooling, the precipitate formed was
washed well with benzene and crystallized from toluene to give N-alkyl-1,2,3,6-tetrahydroquinazoline-2,4-dione9 –13 (cf. Tables 1 and 2 , Scheme 3 ).
(
butylamine, benzylamine, p-aminoacetophenone, p-aminoethylbenzoate (0.1 g, 2 mmol) in glacial acetic acid
or dry toluene for 3 h. After cooling, the precipitate formed was
washed well with benzene and crystallized from toluene to give N-alkyl-1,2,3,6-tetrahydroquinazoline-2,4-dione
