All patients were followed-up regularly. The baseline clinical factors of the two groups of follow-up methods were balanced and comparable .The traditional follow-up group was followed up by telephone interviews and outpatient visits, and the Internet follow-up group was followed up using the mobile medical applications (APP) and WeChat applications. Patients in the traditional follow-up group were followed up by telephone once a month. Follow-up included answering the patients’ questions about SLIT medication, reminding them to take the medication, and asking them about their symptomatic drug use and rhinitis symptoms. Outpatient follow-up was carried out every 3 months. The contents of the follow-up were the same as above, and patients were given renewed prescriptions. In the Internet follow-up group, the Mobile Medical APP was used to publish popular science about AR, distribute and recover questionnaires, remind patients to take the drugs and return to visit and guide patients to evaluate their own efficacy and adjust symptomatic drugs. WeChat was used to push popular health science knowledge, conduct regular live lectures, and facilitate doctor-patient interactions. The details of the follow-up plan are shown in Figure 3. Patients were considered to have poor compliance when they stop taking medication of SLIT.