For the evaluation of glucose tolerance and insulin tolerance, mice of each group were divided into two groups(n = 6), and then separately were intraperitoneal injection of glucose (1 g/kg BW) or insulin (0.75U/kg, Novolin R, Novo Nordisk, Denmark) after overnight fasting. Blood glucose levels were detected from the tail at baseline and 15, 30, 60, 90 and 120 min after injection using a glucose meter (Roche, Germany).
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