Macrophage Culture and CFTR Modulator Assay
Corresponding Organization : The Ohio State University
Other organizations : Mansoura University, Max Planck Unit for the Science of Pathogens, Helwan University, Birzeit University, Nationwide Children's Hospital, Case Western Reserve University
Variable analysis
- Treatment with CFTR modulators
- Concentrations of CFTR modulators (10 µM of tezacaftor (VX-661) and 5 µM of ivacaftor (VX-770))
- In vitro infections
- Primary mouse macrophages (BMDMs) cultured in Iscove's (IMDM media + 10% fetal bovine serum (FBS))
- Positive control: Not explicitly mentioned
- Negative control: Not explicitly mentioned
Annotations
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