The study was approved by the Institutional Review Board at Children’s Hospital Los Angeles. Imaging included fundus photography (Optos California, Optos, Dunferline, Scotland; RetCam 3, Clarity Medical Systems, Pleasanton, CA; Zeiss RESCAN 700 Carl Zeiss Meditec AG, Jena, Germany), fundus autofluorescence (Optos California), fluorescein angiography (RetCam 3), and optical coherence tomography (OCT, Heidelberg Spectralis, Heidelberg, Germany; InVivoVue, Bioptigen, Morrisville, NC, USA). Perioperative 1 mg/kg oral liquid prednisolone was given as described with a 10-day taper.[1 (link)] A total of 0.3 ml VN was delivered via one or two blebs using intraoperative OCT guidance without evidence of reflux followed by full air-fluid exchange.
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Intraoperative OCT-Guided Subretinal Therapy
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Children
Fluorescein angiography
Institutional review board
Optical coherence tomography
Prednisolone
Corresponding Organization : Children's Hospital of Los Angeles
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Variable analysis
independent variables
- Delivery of 0.3 ml VN via one or two blebs using intraoperative OCT guidance without evidence of reflux followed by full air-fluid exchange
- Clinical outcomes (not explicitly mentioned)
- Perioperative 1 mg/kg oral liquid prednisolone with a 10-day taper
- Positive control: Not mentioned
- Negative control: Not mentioned
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