A limitation of the previous Task Force Criteria was the reliance on subjective criteria for assessing ventricular structure and function and for evaluation of myocardial histology. In this modification of the Task Force Criteria, quantitative criteria are proposed and abnormalities are defined based on comparison with normal subject data. (Table 1) The data from 108 probands with newly diagnosed ARVC/D, age 12 years or older, who were enrolled in the National Institutes of Health supported Multidisciplinary Study of Right Ventricular Dysplasia,43 (link) were compared with that of normal subjects. (See appendix) The criteria were selected on the basis of analysis of sensitivity and specificity from ROC curves. For analysis of each test (i.e. echocardiogram, MRI etc.) proband data was excluded if that test was crucial for the diagnosis of the individual patient. This was done to eliminate bias in estimating the sensitivity and specificity of that particular test. In general, when determining the sensitivity and specificity of a new screening test it is recommended that none of the screening test elements are used in making the primary diagnosis; this principle also holds when establishing diagnostic criteria.