Tumor Regression and Surgical Margins

Circumferential resection margin (CRM) was defined as negative if the distance of the tumor from the margin was more than 1 mm. Histopathological tumor regression to neoadjuvant radiotherapy was evaluated according to the Dworak scoring system (15 (link)). The quality of the TME was evaluated using the protocol introduced by Quirke (16 ).

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Albrecht H.C., Wagner S., Sandbrink C, & Gretschel S. (2023). Downsizing of rectal cancer following neoadjuvant radiotherapy (5 × 5 Gy) and long interval surgery evaluated using MRI semiautomated volumetric measurements, a retrospective study. Frontiers in Surgery, 10, 1106177.

Publication 2023

Neoadjuvant radiotherapy Resection margin Tumor

Corresponding Organization : Medizinische Hochschule Brandenburg Theodor Fontane

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Variable analysis

independent variables

Neoadjuvant radiotherapy

dependent variables

Circumferential resection margin (CRM)
Histopathological tumor regression according to the Dworak scoring system
Quality of the TME according to the protocol introduced by Quirke

control variables

Distance of the tumor from the margin (defined as negative if more than 1 mm)

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