Example 1
The target organoselenium compound 5 is synthesized using the Ugi four components reaction. The synthesis starts by the reaction of quinazoline-2-carbaldehyde (1) (1 mmol) with 4-(methylselanyl)aniline (2) (1 mmol) followed by the addition of 2-((3-methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)thio)acetic acid (3) (1 mmol) and 2-isocyano-2-methylpropane (4) (1.2 mmol). The reaction proceeds smoothly at room temperature in methanol as solvent.
It is to be understood that the organic selenide compounds and the use thereof with DPPD are not limited to the specific embodiments described above, but encompasses any and all embodiments within the scope of the generic language of the following claims enabled by the embodiments described herein, or otherwise shown in the drawings or described above in terms sufficient to enable one of ordinary skill in the art to make and use the claimed subject matter.
