Compound Screening for Drug Discovery

Chemicals used in this study were from the following sources: nilotinib (Selleckchem, S1033), imatinib (Selleckchem, S2475), torin1 (Selleckchem, S2827), Gefitinib (MedChemExpress, HY-50895), GSK621 (Sigma, SML2003), EX229 (MedChemExpress, HY-112769), BC1618 (MedChemExpress, HY-134656), bafilomycin A1 (Selleckchem, S1413), MK2206 (Selleckchem, S1078), SRT1720 (Apexbio, A4180–10), FR180204 (Selleckchem, S7524), PLX-4720 (Selleckchem, S1152). PEG300 (Selleckchem, S6704), DMSO (Sigma, D2650).

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Zheng W., Chang I.C., Limberis J., Budzik J., Zha B.S., Howard Z., Chen L, & Ernst J. (2023). Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection. Research Square.

Publication Preprint 2023

nilotinib imatinib torin1 Gefitinib GSK621 EX229 BC1618 bafilomycin A1 MK2206 SRT1720 FR180204 PLX-4720 PEG300 DMSO

Bafilomycin a1 Dmso Fr180204 Gefitinib Gsk621 Imatinib Mk2206 Nilotinib Peg300 Plx 4720 Srt1720

Corresponding Organization : University of California, San Francisco

Other organizations : University of California System

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Variable analysis

independent variables

Nilotinib
Imatinib
Torin1
Gefitinib
GSK621
EX229
BC1618
Bafilomycin A1
MK2206
SRT1720
FR180204
PLX-4720

dependent variables

Not explicitly mentioned

control variables

PEG300

controls

Positive controls not mentioned
Negative controls not mentioned

Annotations

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