CACTI was developed for Project ELICIT, a randomized study of two training methods for motivational interviewing with 190 front-line substance-abuse treatment providers [29] . The software was designed for use with the Motivational Interviewing Skill Code (MISC 2.5) [30] , a sequential-coding system for psychotherapy sessions that was derived from the Sequential Code for Observing Process Exchanges (SCOPE) [31] . The SCOPE uses concurrent transcripts and audio recordings to divide and rate client and clinician speech; it was employed in Project PREMIR [6] (link), a psychotherapy process study of 118 recordings of 13 Motivational Enhancement Therapy clinicians. The MISC 2.5 serves three purposes: parsing (unitizing) speech into codeable utterances (speech units), sequential coding of client and clinician utterances, and assignment of global ratings for clients and clinicians. Multiple versions of the program were tested and refined by trained MISC 2.5 coders before CACTI was employed in Project ELICIT.
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