To update the existing CAMP database (11 (link)), protein data available in NCBI (12 (link)), UniProtKB (13 (link)) and PDB (14 (link)) databases post 2013 was queried using appropriate keywords such as ‘antimicrobial’, ‘antibacterial’, ‘antifungal’, ‘antiviral’ and ‘antiparasitic’. The obtained hits were manually curated to extract information on sequence, structure, protein definition, accession numbers, reference literature, activity, taxonomy of the source organism, target organisms with minimum inhibitory concentration (MIC) values, hemolytic activity of the peptide and protein family descriptions. This information is made available in CAMPR3. Links to UniProtKB, PDB, PubMed (12 (link)) and other databases dedicated to AMPs are also made available for the benefit of the users.
Protocol detail
Expansion and Curation of CAMP Database
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Antibacterial
Antifungal
Antimicrobial
Antiparasitic
Antiviral
Hemolytic
Minimum inhibitory concentration
Peptide
Protein
Corresponding Organization : Indian Council of Medical Research
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Protocol cited in 28 other protocols
Variable analysis
independent variables
- Keywords used for database queries, such as 'antimicrobial', 'antibacterial', 'antifungal', 'antiviral', and 'antiparasitic'
- Sequence
- Structure
- Protein definition
- Accession numbers
- Reference literature
- Activity
- Taxonomy of the source organism
- Target organisms with minimum inhibitory concentration (MIC) values
- Hemolytic activity of the peptide
- Protein family descriptions
- Independent variables not explicitly mentioned.
- Dependent variables not explicitly mentioned.
- Control variables not explicitly mentioned.
- No positive or negative controls were explicitly mentioned in the input protocol.
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