During this background phase, the principal investigator (G.D.S.) and a research assistant (A.G.) reviewed literature and conducted a panel discussion with PCPs and communication experts (n = 5). Based on the findings from this stage, 4 clinical vignettes were developed. The vignettes described the following general medical diagnostic uncertainty scenarios: (1) enlarged lymph node in a patient with a history of lymphoma in remission (ie, worrisome for a recurrence), (2) new-onset headache, (3) fever and upper respiratory infection, and (4) subacute low back pain (eAppendix 2 in Supplement 1).
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