Proteolytic digestion of proteins, fractionation of peptides and mass spectrometric analysis were performed as described previously14 (link). Biological functions were analyzed using the DAVID functional classification tool (https://david.ncifcrf.gov/) and the ClueGO Cytoscape plugin15 (link). Protein array data were obtained using a Phospho Explorer Antibody Array (# PEX100, Full Moon Biosystems, CA, USA).
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