Digital Mammography Imaging Protocols

All CEM scans were performed with a digital mammography unit (Selenia Dimensions, Hologic Inc., Bedford, MA, USA). Iopromide (Ultravist 300, Bayer, Sacramento, CA, USA), at 1.5 mL per kilogram body weight, was injected intravenously using a power injector at a rate of 3 mL/sec. After 2.5 min, the patient was positioned, and all four images (craniocaudal and mediolateral oblique projections of each breast) were acquired within 10 min. For each view, low-energy exposure (28–33 kVp) and high-energy exposure (45–49 kVp) were obtained at the same time in the same compression. For DBT, a conventional X-ray source was used that sweeps along an arc around the breast to acquire multiple two-dimensional digital images.