Unenhanced chest CT scans were performed using a six-row multidetector CT scanner (SOMATOM Emotion 6; Siemens, Erlangen, Germany) with the following parameters: tube voltage, 130 kVp; effective current, 95mA; collimation, 6 x 2 mm, helical pitch, 1.4; field of view, 38 cm; matrix size, 512 x 512. A 1.0-mm thick slice with a 1.0-mm slice increment was reconstructed before analysis. Scanning was performed in the supine position at full inspiration. All patients underwent CT scan within 4 days after symptom onset for symptomatic patients, early to intermediate phase for radiologic manifestations of COVID-19 [14 (link)].
CT image analysis data was performed as per the previously published reports for the patients included in this study [13 (link)]. Evaluation included the following parameters [15 (link)]: the presence or absence of pure ground-glass opacity (GGO), crazy-paving pattern (GGO with inter- or intralobular septal thickening), consolidation, findings compatible with organizing pneumonia (i.e., consolidation with volume loss, subpleural curvilinear lines, and/or reversed halo sign) [16 (link)], and vascular enlargement inside the opacities. The number of affected lobes and anterior or posterior predominance was also recorded.
Free full text: Click here