Example 14

The elemental composition of the Succinic acid-1,4-Butanediol-Malic acid copolyester was analyzed by Proton Induced X-ray Emission (PIXE) at Elemental Analysis Inc. This method provides quantitative elemental composition of a material for inorganic elements sodium through uranium on the periodic table. The elements found are shown in Table 7. The polymer did not contain detectable heavy metals such as Tin, which is sometimes used in the manufacture of resorbable polymers such as poly-glycolide, polylactide and poly-glycolide-co-lactide. The following trace elements were detected: silicon 18.98 ppm, titanium 14.77 ppm, and zinc 5.967 ppm.

TABLE 7
PIXE Analysis of a Poly(butylene succinate) Polymer
ElementEnergyDet. LimitConcentration
Name(keV)95% Conf.MassError
Silicon1.7408.964 ppm18.980 ppm5.056 ppm
Titanium4.5112.362 ppm14.770 ppm2.057 ppm
Zinc8.6390.457 ppm 5.967 ppm0.544 ppm

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