Diagnosis and Treatment of Lean MAFLD
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Corresponding Organization :
Other organizations : Mengchao Hepatobiliary Hospital, Fujian Medical University, Weatherford College
Variable analysis
- BMI (≥ 23 kg/m^2 or < 23 kg/m^2)
- Metabolic dysregulation (presence of 2 or more abnormalities: high waist circumference, hypertension, abnormal levels of plasma triglycerides or cholesterol, prediabetes or insulin resistance and high level of plasma high-sensitivity C-reactive protein)
- Hepatic steatosis (>5%, detected by postoperative liver histopathology)
- Lean-MALFD (MAFLD with BMI < 23kg/m^2)
- Hepatectomy (complete resection of all microscopic and macroscopic tumors with negative histologic resection margin)
- Cirrhosis and hepatic steatosis (determined directly by imaging or postoperative hepatic histopathology)
- Severity of complications (graded using Dindo–Clavien classification)
- Major complications (Clavien classification ≥ III, including infectious complications)
- Postoperative death (death from a postoperative complication within 30 days after hepatectomy)
- Alcohol consumption (male ≥ 30 g/day, female ≥ 20 g/day)
- HBV infection (evidence of hepatitis B surface antigen-positive and/or HBV DNA-positive)
- HBV-HCC (HCC caused by HBV infection)
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