Standard protocol non-contrast cardiac-gated CT scans for CAC scoring were performed. Electron beam tomography was used in 93% of scans, while multi-detector CT (MDCT) was performed in 7% of scans. Previously no clinically significant difference in CAC scoring has been demonstrated between these scanning technologies (15 (link)). In this analysis, approximately 13% of patients were scanned with the Imatron C-100 scanner, 38% with the Imatron C-150, 38% with the C-300 and 3.5% with the e-speed scanner (GE-Imatron). The rest of the scans (7%) were performed on a 4-slice MDCT scanner (Somatom Volume Zoom, Siemens) and the General Electric LightSpeed VCT 64-slice platform (GE Healthcare). This has been previously described in the CAC consortium design and rationale (13 (link)). CAC was quantified in Agatston units in all participants and considered prevalent if CAC >0 and also categorized as CAC 0, CAC 1-99, 100-399, and CAC ≥ 400.
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Standardized Cardiac CT Imaging for CAC Scoring
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Corresponding Organization :
Other organizations : Minneapolis Heart Institute Foundation, Cornell University, St. Luke's Hospital, Icahn School of Medicine at Mount Sinai, Cedars-Sinai Smidt Heart Institute, UCLA Medical Center, Harbor–UCLA Medical Center, Yale University
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Variable analysis
independent variables
- Scanning technology (electron beam tomography vs. multi-detector CT (MDCT))
- Coronary artery calcium (CAC) score
- Prevalence of CAC (CAC > 0)
- CAC categories (CAC 0, CAC 1-99, 100-399, CAC ≥ 400)
- Cardiac-gated CT scans for CAC scoring
- Agatston units for CAC quantification
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