Categorical and continuous variables were compared between patients with and without significant fibrosis using Chi-squared and Student’s t-test or the Wilcoxon rank-sum test (according to the distribution of the data), respectively. Most of the numerical values did not follow a normal distribution and were expressed as medians and interquartile ranges. The diagnostic performance of each scoring system was then evaluated using receiver operating characteristic curves, and comparisons between the correlated AUROCs were performed using DeLong’s test[17 (link)]. The sensitivities (Sens) and specificities (Spec) of each scoring system were analyzed using the given low and high cutoffs for predicting F2, as reported previously-i.e., 0.88 and 1.77 for the FIB-8 score, 0.81 and 1.81 for the FIB-4 score, and -2.45 and 0.03 for the NFS, respectively[11 ,18 (link)]. All statistical analyses were performed using the SPSS statistical analysis package (version 18.0.0; SPSS Inc., Chicago, Illinois, United States), Stata (version 15; StataCorp), and R program version 4.1.1. A P value < 0.05 was considered statistically significant.