Intussusception Incidence, Age, and CFR

We compiled a database containing information on intussusception incidence rates, age distributions and CFRs in children aged <5 years. For all studies, we extracted the country, subnational location, study design, case definition, period of data collection and age range. To obtain more granular age distributions, we emailed an invitation letter to all authors who were listed in the Jiang et al. review (2002–12)³ (link) and all authors identified in the new systematic review (2012–18). We invited each author to share a spreadsheet table with counts of intussusception hospital admissions by week of age up to 5.0 years. If the authors did not respond, then we extracted the age distributions published in the research article. We also extracted the published incidence rate and the number of intussusception cases and deaths.
A country dataset was defined as any dataset with hospitalized patients before the introduction of rotavirus vaccine, taken from a single study in a single country and reporting on a single outcome, e.g. age distribution, incidence rate and CFR. If a study included multiple years and multiple sites, then all pre-vaccination years and subnational sites were aggregated and included in the same country dataset. The main outcome/presentation was hospital admissions, but we also included emergency room visits if admissions were not reported in the same study.