SERVE-HF participants were randomly assigned to receive guideline-based medical treatment alone (control) or guideline-based medical treatment with ASV (Auto Set CS, ResMed). Full details of ASV titration and settings have been reported previously (10 (link)). Substudy evaluations such as PSG were performed at baseline, and at 3 and 12 months after randomization. The substudy was completed when all 312 patients had been followed for 12 months.
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