Idiopathic Overactive Bladder Study

Forty-nine women, aged >18 years, with idiopathic OAB were included in this study. Additional inclusion criteria were OAB combined with urge, >8 mictions per day, and nocturia ≥2 voids/night, hence disrupted sleep. Patients who did not fulfil all the inclusion criteria were excluded. Further exclusion criteria were neurogenic hyperactive bladder, hypersensitivity to the study drug or its active compound or to drugs similar to the study drug, lactose intolerance, and the intake of bladder active drugs (anticholinergics, diuretics, bladder relaxing drugs including other phytomedicines) less than 4 weeks prior to study begin. Further exclusion criteria were acute UTI, pregnancy or lactation, drug or alcohol abuse, malcompliance, and participation in another study (current or during the last 4 weeks prior to inclusion in this study). Local systemic HRT was acceptable when started more than 4 weeks before study enrolment. A prior incontinence operation had to date back more than 6 months. Study information and informed consent were available only in German; hence, only German-speaking women were enrolled.