Formulation and evaluation of paracetamol tablets

The gum of Acacia etbaica was collected from Klte Awulaelo district, Eastern Zone of Tigray region; paracetamol (batch no. 1706003, HEDEI JIHENG, Pharmaceuticals, Germany), PVP K-30 (BOAINKY, Pharmaceutical Ltd., India), and Acacia BP (batch no. 242, BOAINKY, Pharmaceutical Ltd., India) were kindly donated from Addis Pharmaceutical Factory Sh. Co. Lactose, magnesium stearate, potassium dihydrogen phosphate, sodium hydroxide, sodium chloride, sodium hydrogen phosphate dehydrate, acetone, HCl (LOBA CHEMIE PVT. LTD, England), maize starch (DBEBATS, India), talc (SISCO LAB, India), ethanol (Batch no. 026193, Fine Chemical General Trading, Ethiopia), and chloroform (CHEMIE PVT. LTD., England) were purchased from local market. All the chemicals were analytical grade and used as received.

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Desta K.H., Tadese E, & Molla F. (2021). Physicochemical Characterization and Evaluation of the Binding Effect of Acacia etbaica Schweinf Gum in Granule and Tablet Formulations. BioMed Research International, 2021, 5571507.

Publication 2021

Lactose magnesium stearate acetone HCl

Acacia Acacia gum Acetone Chloroform Ethanol Hydrogen Lactose Magnesium stearate Maize starch Paracetamol Pharmaceutical Potassium dihydrogen phosphate Sodium chloride Sodium hydroxide Sodium phosphate Talc

Corresponding Organization : Wollo University

Other organizations : Mekelle University

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Protocol cited in 3 other protocols

Variable analysis

independent variables

Acacia etbaica gum
Paracetamol
PVP K-30
Acacia BP

dependent variables

Not explicitly mentioned

control variables

Lactose
Magnesium stearate
Potassium dihydrogen phosphate
Sodium hydroxide
Sodium chloride
Sodium hydrogen phosphate dehydrate
Acetone
Maize starch
Ethanol
Chloroform

positive controls

None specified

negative controls

None specified

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