Neoadjuvant Therapy Pathological Response

The primary endpoint was the percentage of pathological complete remissions (pCRs), which was assessed locally at the time of surgery and defined as the absence of invasive tumor cells in the breast and axilla (pCR; ypT0/Tis, ypN0). Patients underwent breast-conserving or ablative surgery, and treatment of axillary lymph nodes included sentinel lymph node biopsy or axillary lymph node dissection.

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Chen H., Maimaitiaili A., Liu Z., Ling R., Zhao Y., Yang H., Liu Y., Liu K., Zhang J., Mao D., Yu Z., Liu Y., Fu P., Wang J., Jiang H., Zhao Z., Tian X., Cao Z., Wu K., Song A., Jin F., He J., Fan Z, & Zhang H. (2023). Efficacy analysis of neoadjuvant chemotherapy with or without anthracyclines in female patients with HER2-positive breast cancer in China: a nationwide, multicenter, 10-year retrospective study (CSBrS-012). Therapeutic Advances in Medical Oncology, 15, 17588359231156146.

Publication 2023

Axillary Breast Cells Lymph node dissection Lymph nodes Patients Sentinel lymph node biopsy Surgery Tumor

Corresponding Organization : First Affiliated Hospital of Xi'an Jiaotong University

Other organizations : Zhengzhou University, Henan Cancer Hospital, Air Force Medical University, Xijing Hospital, China Medical University, University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hebei Medical University, Fourth Hospital of Hebei Medical University, Jilin Province Tumor Hospital, Harbin Medical University, Second Affiliated Hospital of Harbin Medical University, Guiyang Medical University, Affiliated Hospital of Guizhou Medical University, Second Hospital of Shandong University, Peking University First Hospital, Peking University, Zhejiang University, Chinese PLA General Hospital, Capital Medical University, Second Affiliated Hospital of Dalian Medical University, Dalian Medical University, Shandong Provincial Hospital, Shandong University, Inner Mongolia People's Hospital, Obstetrics and Gynecology Hospital of Fudan University, Lanzhou University, Lanzhou University Second Hospital, First Hospital of China Medical University, First Hospital of Jilin University, Jilin University

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Variable analysis

independent variables

Type of surgery (breast-conserving or ablative)

dependent variables

Percentage of pathological complete remissions (pCRs)

control variables

Treatment of axillary lymph nodes (sentinel lymph node biopsy or axillary lymph node dissection)

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