SNS consists of Chaihu (Radix Bupleuri Chinensis, derived from Bupleurum chinense DC, voucher number 16012002), Baishao (Radix Paeoniae Alba, derived from Paeonia lactiflora Pall, voucher number 16040201), Zhishi (Fructus Aurantii Immaturus, derived from Citrus aurantium L, voucher number 16011370), and Gancao (Radix Glycyrrhizae, derived from Glycyrrhiza uralensis Fisch, voucher number 15091001) with a ratio of 1:1:1:1.
These raw herbs were purchased from Beijing Xinglin Pharmaceutical Company and were identified as eligible medicinal material. SNS was prepared by the Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University. Specifically, a total weight of 400 g of the above raw herbs was mixed and impregnated in 2400 ml distilled water for 30 min. Then the medical materials were boiled for 30 min and 400 ml SNS preparation was harvested. This procedure was repeated, and a final volume of 800 ml was obtained from each 400 g herbs. The decoction was stored at 4 °C until the experiment. The major components of SNS decoction were saikosaponins, peoniflorin, naringin and glycyrrhizic acid [10 (link)–12 (link)].
These raw herbs were purchased from Beijing Xinglin Pharmaceutical Company and were identified as eligible medicinal material. SNS was prepared by the Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University. Specifically, a total weight of 400 g of the above raw herbs was mixed and impregnated in 2400 ml distilled water for 30 min. Then the medical materials were boiled for 30 min and 400 ml SNS preparation was harvested. This procedure was repeated, and a final volume of 800 ml was obtained from each 400 g herbs. The decoction was stored at 4 °C until the experiment. The major components of SNS decoction were saikosaponins, peoniflorin, naringin and glycyrrhizic acid [10 (link)–12 (link)].
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