A 5-French catheter was inserted into the common hepatic artery via the right femoral artery. Before steroid injection, angiography was performed to detect any anomalies in the hepatic artery. If no replaced hepatic artery was found, the tip of the catheter was set at the proper hepatic artery. If there were 2 hepatic arteries, the catheter was positioned in the branch with the most expansive feeding area. After insertion, 1000 mg of methylprednisolone was infused over 1 hour each day for 3 days, and the catheter was removed immediately after injection on the third day. A once-daily plasma exchange was added to the regimen if a bleeding tendency was observed during this procedure.
Protocol detail
Hepatic Artery Catheterization for Steroid Infusion
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Angiography
Bleeding tendency
Catheter
Femoral artery
Hepatic arteries
Methylprednisolone
Plasma exchange
Regimen
Steroid
Corresponding Organization : Kyushu University
Other organizations : Kyushu University Hospital, Nakamura Gakuen University
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Variable analysis
independent variables
- Catheter type (5-French catheter)
- Catheter insertion site (right femoral artery)
- Catheter placement (common hepatic artery, proper hepatic artery, or branch with most expansive feeding area)
- Steroid administration (1000 mg of methylprednisolone infused over 1 hour each day for 3 days)
- Presence of any anomalies in the hepatic artery (detected by angiography)
- Bleeding tendency during the procedure
- Catheter removal (immediately after injection on the third day)
- Plasma exchange (once-daily, added to the regimen if a bleeding tendency was observed)
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