Targeted Somatic Mutation Detection in CTCs
Corresponding Organization :
Other organizations : Universität Hamburg, University Medical Center Hamburg-Eppendorf
Variable analysis
- Targeted detection of somatic mutations in CTCs and tissue
- Mutation signal produced using iPLEX HS chemistry
- Ability to reliably detect mutation signal at about 1% VAF
- Use of the MALDI-TOF based MassARRAY System (Agena Bioscience, San Diego, California)
- Use of the Lung Panel covering 70 mutations in five key oncogenes (BRAF, EGFR, ERBB2, KRAS and PIK3CA)
- Positive control: Not explicitly mentioned
- Negative control: Not explicitly mentioned
Annotations
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