STZ (Sigma) was freshly dissolved in 0.1 M sodium citrate buffer (pH 4.5) at a dose of 65 mg/kg body weight. The STZ dose was chosen based on the previous studies [6 (link),35 (link)]. EGCG (Sigma) was dissolved in sterile distilled water and administered orally at a dose of 40 mg/kg/day of EGCG (Sigma) one week after STZ injection. The dose of EGCG was chosen based on a previous study [36 (link)].
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