Spectroscopic Characterization of NB Compounds

Details on the preparation and spectroscopic characterization of NB compounds were previously described [29 (link)]. NB-73, NB-115, Thiostrepton (Sigma-Aldrich #598226), FDI-6 (Sigma-Aldrich #SML1392), RCM-1 (R&D Systems, Minneapolis, MN, USA, #6845), N-phenylphenanthren-9-amine (Sigma-Aldrich, St. Louis, MO, USA, #761966), MG132 (Sigma-Aldrich #474790), Q-VD-OPh (R&D Systems #OPH001), and olaparib (Selleck Chemicals, Houston, TX, USA, #S1060) were dissolved in DMSO. NB-55 and monensin (R&D Systems #5223) were dissolved in ethanol. Carboplatin (Sigma-Aldrich #C2538) was dissolved in water. All compounds were stored at -20 °C.

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Liu C., Vorderbruggen M., Muñoz-Trujillo C., Kim S.H., Katzenellenbogen J.A., Katzenellenbogen B.S, & Karpf A.R. (2024). NB compounds are potent and efficacious FOXM1 inhibitors in high-grade serous ovarian cancer cells. Journal of Ovarian Research, 17, 94.

Publication 2024

Thiostrepton FDI-6 MG132 Q-VD-OPh olaparib monensin Carboplatin

Corresponding Organization :

Other organizations : University of Nebraska Medical Center, University of Illinois Urbana-Champaign

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Variable analysis

independent variables

NB-73
NB-115
Thiostrepton
FDI-6
RCM-1
N-phenylphenanthren-9-amine
MG132
Q-VD-OPh
Olaparib
NB-55
Monensin
Carboplatin

dependent variables

Not explicitly mentioned

control variables

All compounds were stored at -20 °C

positive controls

Not explicitly mentioned

negative controls

Not explicitly mentioned

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