After screening the related studies in the databases, all included diagnostic trials needed to meet the following inclusion and exclusion criteria. Inclusion criteria were as follows: the study population were cases with a confirmed diagnosis of breast cancer; diagnostic methods used were mammography or MRI; the gold standard for diagnosis of breast cancer was pathological examination; Include high-risk factors: BRCA1 or BRCA2 mutation carriers, personal or family history of breast or ovarian cancer, history of prior chest radiation. Exclusion criteria were as follows: case report or review study type; patients had obvious symptoms of breast cancer during screening; and duplicated publication or data.
Protocol detail
Breast Cancer Diagnostic Accuracy
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Brca1
Brca2
Breast
Breast cancer diagnosis
Cancer of breast
Chest
Diagnosis
Gold
Mammography
Mutation
Ovarian cancer
Patients
Radiation
Corresponding Organization : Shaoxing Second Hospital
Other organizations : Shaoxing University, Shaoxing City Women and Children Hospital
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Variable analysis
independent variables
- Diagnostic methods used (mammography or MRI)
- Diagnosis of breast cancer
- Study population with confirmed diagnosis of breast cancer
- Gold standard for diagnosis of breast cancer was pathological examination
- High-risk factors (BRCA1 or BRCA2 mutation carriers, personal or family history of breast or ovarian cancer, history of prior chest radiation)
- Positive control: Pathological examination as the gold standard for diagnosis of breast cancer
- Negative control: Exclusion of patients with obvious symptoms of breast cancer during screening
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