Patients were recruited from two dialysis centres in Eastern Denmark. All patients aged 18 years or older with end-stage kidney disease (ESKD) treated with chronic HD via a central venous catheter (CVC) or arteriovenous (AV) fistula were screened for participation. Exclusion criteria were inability to give informed consent, known intolerance to β-lactam antibiotics or clindamycin, active infection treated with antibiotics <7 days prior to inclusion, breastfeeding or pregnancy. Data on the cause of kidney failure, HD filter type, HD flow, HD time, height, weight, smoking status, alcohol consumption and comorbidities were recorded.
Protocol detail
Hemodialysis Patients Recruitment Protocol
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Antibiotics
Arteriovenous fistula
Central venous catheter
Clindamycin
Dialysis
End stage kidney disease
Infection
Kidney failure
Lactam antibiotics
Patients
Pregnancy
Corresponding Organization : University of Copenhagen
Other organizations : Copenhagen University Hospital, Rigshospitalet, Gentofte Hospital, Aarhus University Hospital
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Variable analysis
independent variables
- HD filter type
- HD flow
- HD time
- Cause of kidney failure
- Height
- Weight
- Smoking status
- Alcohol consumption
- Comorbidities
- Patients aged 18 years or older with end-stage kidney disease (ESKD) treated with chronic HD via a central venous catheter (CVC) or arteriovenous (AV) fistula
- Ability to give informed consent
- No known intolerance to β-lactam antibiotics or clindamycin
- No active infection treated with antibiotics <7 days prior to inclusion
- Not breastfeeding or pregnant
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