T1-weighted MRI Acquisition Methods

T₁-weighted data were obtained on multiple 3T scanners in the ABCD Study (Siemens Prisma, General Electric (GE) 750 and Philips) and one scanner in the Generation R Study (GE 750). Standard adult-sized coils were used for the ABCD Study and an eight-channel receive-only head coil for the Generation R Study. To acquire T₁-weighted structural images, the ABCD Study used an inversion prepared RF-spoiled gradient echo scan with prospective motion correction while the Generation R Study used an inversion recovery fast spoiled gradient recalled sequence (GE option = BRAVO, TR = 8.77 ms, TE = 3.4 ms, TI = 600 ms, flip angle = 10°, matrix size = 220 × 220, field of view = 220 × 220 mm, slice thickness = 1 mm, number of slices = 230, ARC acceleration factor = 2). More details can be found elsewhere (Casey et al., 2018 (link); Hagler et al., 2019 (link); White et al., 2018 (link)). Of note, in the ABCD Study, a technical mistake occurred at one collection site, causing the hemisphere data to be flipped. This was fixed before processing.

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Dall'Aglio L., Kim H.H., Lamballais S., Labrecque J., Muetzel R.L, & Tiemeier H. (2022). Attention-deficit hyperactivity disorder symptoms and brain morphology: Examining confounding bias. eLife, 11, e78002.

Publication 2022

Prisma GE 750

Acceleration Adult Echo Electric Head Inversion Prisma Scan

Corresponding Organization : Boston University

Other organizations : Erasmus University Rotterdam

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Variable analysis

independent variables

Scanner type (Siemens Prisma, General Electric (GE) 750, Philips)

dependent variables

T1-weighted structural images

control variables

Standard adult-sized coils for the ABCD Study
Eight-channel receive-only head coil for the Generation R Study
Inversion prepared RF-spoiled gradient echo scan with prospective motion correction for the ABCD Study
Inversion recovery fast spoiled gradient recalled sequence (GE option = BRAVO, TR = 8.77 ms, TE = 3.4 ms, TI = 600 ms, flip angle = 10°, matrix size = 220 × 220, field of view = 220 × 220 mm, slice thickness = 1 mm, number of slices = 230, ARC acceleration factor = 2) for the Generation R Study

other notes

A technical mistake occurred at one collection site in the ABCD Study, causing the hemisphere data to be flipped. This was fixed before processing.

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