DNCB-Induced Atopic Dermatitis in Mice
Corresponding Organization : Korea University of Science and Technology
Other organizations : Chonnam National University
Variable analysis
- Treatment with VAE (100 and 300 mg/kg)
- Treatment with dexamethasone (DX, 5 mg/kg)
- Development of DNCB-induced atopic dermatitis-like symptoms
- Age of mice (6 weeks old)
- Sex of mice (female)
- Mouse strain (BALB/c)
- Housing conditions (ad libitum access to food and water, 12 h light-dark cycle, controlled temperature)
- Sensitization protocol (20 μL of DNCB applied once to each ear in the first week)
- Challenge protocol (both ears challenged with 1% DNCB, 20 μL/ear, once per week for 3 weeks)
- Negative control: Vehicle phosphate-buffered saline (PBS)
- Negative control: DNCB vehicle (PBS)
Annotations
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