In accordance with the American Thoracic Society/European Respiratory Society guidelines, all participants underwent post-bronchodilator spirometry (VMAX 22 spirometer; Sensormedics, Yorba Linda, CA).[15 (link)] The participants inhaled 400 μg salbutamol 20 minutes before testing. We measured FVC, FEV1, and FEV1/FVC ratio.
The peak cough flow (PCF) was assessed using an Asthma Mentor Peak Flow Meter (Respironics, Murrysville, PA).[16 ] Participants performed a quick and explosive expiration after maximal inspiration in the sitting position. The average value from the three tests was calculated.