URB597 (0.1 and 0.3 mg/kg; Sigma-Aldrich, UK) was solubilized in 5% polyethylene glycol (Fluka Chemicals, Switzerland), 5% Tween 80 (Sigma-Aldrich) and 90% saline; doses and protocols were based on previous findings (31 (link)–33 (link), 41 (link)). Rats received either one of the URB597 doses or vehicle per experiment. All injections were administered intraperitoneally (1 ml/kg) and were given 30 min before testing.
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