The preparation of a blend PLCL/PLC nanofibrous membrane (NF) was described earlier.17 (link) Briefly, the nanofibrous blend of poly(L-lactide-co-ɛ-caprolactone) (PLCL) and poly(ε-caprolactone) (PCL) was prepared by an electrospinning technique (Nanospider NS 1WS500U; Elmarco) at the Technical University of Liberec. The PLCL/PLC blend (1:1) of biodegradable polymers with 0.46–2.48 µm was prepared by mixing 5% of (w/w) PLCL (Purasorb PLC 7015, Corbion, Amsterdam, Netherlands) with 5% (w/w) PCL (PCL; Mn 80,000 g/mol; Merck, Darmstadt, Germany) in a chloroform/ethanol solution (8:2).
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Fabrication of PLCL/PLC Nanofibrous Membrane
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Corresponding Organization :
Other organizations : Czech Academy of Sciences, Institute of Macromolecular Chemistry, Universitat Autònoma de Barcelona, Czech Academy of Sciences, Czech Academy of Sciences, Institute of Physiology, Technical University of Liberec
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Variable analysis
independent variables
- Ratio of PLCL to PCL (1:1)
- Nanofibrous blend diameter (0.46-2.48 µm)
- Concentration of PLCL (5% w/w)
- Concentration of PCL (5% w/w)
- Solvent composition (chloroform/ethanol, 8:2)
- Electrospinning technique (Nanospider NS 1WS500U; Elmarco)
- No positive or negative controls were explicitly mentioned.
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