Homogenization and Sonication of Lipid Nanocarriers
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Corresponding Organization :
Other organizations : Chang Gung Memorial Hospital, Chang Gung University, Chang Gung University of Science and Technology, Ming Chi University of Technology
Variable analysis
- High-shear homogenization at 12,000 rpm for 20 min
- Ultrasonication at 35 W and 20 amplitudes for 15 min
- Characteristics of the final NLC product
- Lipid matrix composition (6% palmityl palpitates, 1% soy phosphatidylcholine, 6% OA)
- Aqueous solution composition (3.5% pluronic F68, 83.5% ddH2O)
- Temperature of lipid matrix and aqueous solution (85 °C)
- No positive or negative controls are explicitly mentioned.
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