Serum levels of total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), oxidized LDL (OX-LDL), and very low-density lipoprotein (VLDL); aspartate transaminase (AST) and alanine transaminase (ALT) were measured using commercial assay kits purchased from Jiancheng Bioengineering Institute (Nanjing, China). Cardio risk index analysis: TC/HDL-C, cardiac risk ratio 1; LDL-C/HDL-C, cardiac risk ratio 2; atherogenic index were determined using the Ikewuchi equation [35] . MDA concentration was measured using commercial assay kits from Beyotime Biotechnology (China). The levels of tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and C-reactive protein (CRP) in the serum were quantified by the enzyme-linked immunosorbent assay (ELISA) kit (Elab-science Biotechnology Co., Ltd).