rsEEG was collected using Brain Products EEG systems (Brain Products, Gilching, Germany) at two UBC sites part of the Canadian Biomarker Integration Network in Depression (Lam et al., 2016 (link)). The process of acquiring data with different systems has been carefully considered and addressed (Farzan et al., 2017a (link)). Continuous rsEEG was recorded using 31 (site A) or 64 (site B) recording sites determined using the 10–20 system of electrode placement, an EasyCap electrode cap, and sintered Ag-AgCl electrodes. rsEEG data were recorded using a QuickAmp amplifier (Brain Products, Gilching, Germany; 1000 Hz A/D rate; 0.10 Hz high pass, 499 Hz low pass; common average reference; impedances ≤ 10 kΩ). rsEEG was obtain within 7 days of treatment initiation in all participants (mean 3.7 days).
Participants were given the same resting state instructions, “Please close your eyes for 3 min while we collect your brain activity at rest. Let your mind wander and try not to fall asleep.” All rsEEGs were conducted in a sound-attenuated room with reduced lighting to limit distraction and noise. Two sets of bipolar electrodes were placed around the participant’s eyes for collecting Electrooculogram (EOG) to track eye movements for artifact rejection.
Participants were given the same resting state instructions, “Please close your eyes for 3 min while we collect your brain activity at rest. Let your mind wander and try not to fall asleep.” All rsEEGs were conducted in a sound-attenuated room with reduced lighting to limit distraction and noise. Two sets of bipolar electrodes were placed around the participant’s eyes for collecting Electrooculogram (EOG) to track eye movements for artifact rejection.
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