Standardized Anesthesia and Multimodal Analgesia Protocols
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Corresponding Organization : Zhejiang Chinese Medical University
Variable analysis
- Sufentanil 0.5 μg/kg, midazolam 0.04 mg/kg, propofol 1 to 2 mg/kg, and Cisatracurium 2 μg/kg intravenously
- Continuous intravenous infusion of remifentanil 0.1 to 0.3 μg/(kg·min), propofol 2 to 5 mg/(kg·hr) and inhalation of sevoflurane to maintain anesthesia
- Oral celecoxib restarted since postoperative day 1 till postoperative 3 weeks
- Spinal-epidural (subarachnoid mepivacaine, 45–60 mg)
- Adductor canal block (ultrasound-guided; 15 cc bupivacaine, 0.25%, with 2 mg preservative-free dexamethasone)
- 4 doses of 1000 mg IV acetaminophen every 6 hours followed by 1000 mg oral acetaminophen every 8 hours
- 4 doses of 15 mg IV ketorolac followed by 15 mg meloxicam every 24 hours
- 5 to 10 mg oral oxycodone as needed for pain
- Postoperative intravenous patient-controlled anesthesia (PCA) pump that administered 1 mL of a 100-mL mixture containing 2000 mg of fentanyl on demand
- Intravenous PCA encompassing delivery of 1 mL of a 100 mL solution containing 2000 µg of fentanyl postoperatively
- Spinal anesthesia consisting of an intrathecal dose of bupivacaine 10 to 12.5 mg with fentanyl 10 mg
- Intravenous injection of morphine with PCA (1 mg bolus, 5 minutes lockout time, and a maximum hourly limit of 8 mg)
- Acetaminophen 1 g 6 hourly
- Not explicitly mentioned
- Standardized general anesthesia and basic analgesic protocol
- Standardized anesthetic and multimodal analgesic protocol
- Standard intraoperative and postoperative multimodal anesthetic protocol
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