Starting from 1-(2-aminoethyl)-piperazine (129 mg), yield =64.4%. 1H NMR (400 MHz, CDCl3), δ (ppm): 2.39–2.52 (m, 8H, piperazine), 2.60 (t, 2H, J = 6.7 Hz, phthalimide-CH2CH2N), 3.44 (s, 2H, NCH2Ph) 3.78 (t, 2H, J = 6.7 Hz, phtalimide–CH2CH2N), 7.19–7.27 (m, 5H, aromatics, Ph–CH2), 7.67–7.69 and 7.80–7.82 (m, 4H, phtalimide); m/z (ESI-MS): 350 (M + H)+.
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Synthesis of Phthalimide-Functionalized Benzylamine
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Corresponding Organization : University of Lisbon
Other organizations : University of Bari Aldo Moro, University of Coimbra
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- Starting from 1-(2-aminoethyl)-piperazine (129 mg)
- Yield = 64.4%
- 1H NMR (400 MHz, CDCl3), δ (ppm): 2.39–2.52 (m, 8H, piperazine), 2.60 (t, 2H, J = 6.7 Hz, phthalimide-CH2CH2N), 3.44 (s, 2H, NCH2Ph) 3.78 (t, 2H, J = 6.7 Hz, phtalimide–CH2CH2N), 7.19–7.27 (m, 5H, aromatics, Ph–CH2), 7.67–7.69 and 7.80–7.82 (m, 4H, phtalimide); m/z (ESI-MS): 350 (M + H)+
- Not explicitly mentioned
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