Preparation of Detergent-Solubilized Lipid Micelles
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Corresponding Organization :
Other organizations : Washington University in St. Louis, NIST Center for Neutron Research, National Heart Lung and Blood Institute, University of Iowa
Variable analysis
- Type of lipid mixture used: 1) E. coli polar lipid extract, 2) 0.67 POPE/0.33 POPG (2:1 POPE/POPG), or 3) 0.67 POPE/0.23 POPG/0.1 bovine cardiolipin
- Detergent solubilized lipid micelles
- Concentration of lipid stock solution (25 mg/mL)
- Concentration of lipid in resuspension buffer (20 mg/mL)
- Concentration of CHAPS detergent (35 mM)
- Buffer composition (300 mM KCl, 20 mM citrate pH 4.5)
- Evaporation and washing steps to prepare the lipid film
- Use of 0.22-μm filtered Ultra High Purity N2 gas
- No positive or negative controls were explicitly mentioned.
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