CCM samples were measured on a QSTAR Elite (AB Sciex, Darmstadt, Germany) coupled to a Dionex Ultimate 3000 pump (Thermo Fisher Scientific) as described previously [31 (link)]. TIF samples were analyzed on a Q Exactive Plus (Thermo Fisher Scientific) coupled to an EASY-nLC 1000 liquid chromatograph (Thermo Fisher Scientific) as described before [32 (link)]. Mass spectrometers were operated in data-dependent mode for MS and MS/MS.
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