C57BL/6 (B6) male mice were purchased from Taconic (Ejby, Denmark). IFNAR−/− mice were kindly provided by B. Johansson-Lindbom, Lund University (Lund, Sweden). B6.E2-2fl/fl mice were generated as previously detailed [23 (link)] and B6.Cg-Tg(Itgax-cre)1-1Reiz/J mice were purchased from Jackson Laboratory (Bar Harbor, ME, USA). B6.E2-2fl/fl and B6.Cg-Tg(Itgax-cre)1-1Reiz/J mice were paired; the offspring were screened for flox-sites and cre-recombinase and were bred to produce the B6.E2-2fl/flItgax.cre+ and B6.E2-2fl/flItgax.cre− mice used in this study.
B6.E2-2fl/flItgax.cre mice were bred in a specific pathogen-free animal facility at Lund University and kept under standard conditions with ad libitum access to water and food during experiments. The experiments were conducted in compliance with the National Institutes of Health guidelines, and all animal experimental procedures were approved by the ethical committee of Lund University Animal Care and Use.
B6.E2-2fl/flItgax.cre mice were bred in a specific pathogen-free animal facility at Lund University and kept under standard conditions with ad libitum access to water and food during experiments. The experiments were conducted in compliance with the National Institutes of Health guidelines, and all animal experimental procedures were approved by the ethical committee of Lund University Animal Care and Use.
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