Benzothiophene-3-carboxaldehyde Hydrazine Synthesis

Benzothiophene-3-carboxaldehyde (1 mmol) was reacted with 4-bromophenyl hydrazine hydrochloride (1.2 mmol) in 20 ml of absolute ethanol in the presence of 0. : 109.38; 113.78; 123.00; 124.61; 125.05; 125.12; 128.53; 131.79; 131.87; 134.90; 135.62; 140.17; 144.63 (azomethine C) ; ESI MS m/z 331(M+,%100),333(M+2, %90).

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Gürsoy Ş., Çaka Z., Faydalı N., Shirinzadeh H., & Dilek E. (2024). Exploring Novel Schiff Base Compounds Derived from Benzothiophene-3- carboxaldehyde Hydrazones: In vitro and In silico Evaluation as Potential Inhibitors of Cholinesterases and Carbonic Anhydrases I-II. Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 17(1), 174-195.

Publication 2024

Corresponding Organization :

Other organizations : Erzincan University, Selçuk University

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Variable analysis

independent variables

Benzothiophene-3-carboxaldehyde (1 mmol)
4-bromophenyl hydrazine hydrochloride (1.2 mmol)

dependent variables

NMR peaks at 109.38; 113.78; 123.00; 124.61; 125.05; 125.12; 128.53; 131.79; 131.87; 134.90; 135.62; 140.17; 144.63 (azomethine C)
ESI MS m/z 331(M+,%100),333(M+2, %90)

control variables

20 ml of absolute ethanol

Annotations

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