All dogs underwent an MRI scan of the brain with a 3 Tesla MRI (Philips Ingenia scanner, Philips AG, Zurich, Switzerland) and a 16-channel receive–transmit head coil (dStream HeadSpine coil solution, Philips AG, Zurich, Switzerland) under general anesthesia with a standardized anesthetic protocol (16 (link)).
Conventional morphological MR images included T2-weighted (T2W) turbo spin-echo sequences in transverse, dorsal, and sagittal planes, a transverse fluid-attenuated inversion recovery (FLAIR), a transverse T2* or a susceptibility-weighted sequence, and a 3D T1W gradient echo sequence.
In the dogs with idiopathic epilepsy, the 3D T1W sequence was repeated after intravenous injection of contrast media [Gadodiamide (Omniscan) GE HealthcareAG, Glattbrugg, Switzerland, or Gadoteric-acid (Dotarem), Guerbet AG, Zürich, Switzerland].
The echo-planar DTI sequence was performed in a transverse plane (TR 8,191 ms; TE 81 ms) with 32 diffusion directions (single low b value = 0 s/mm2; maximal b value = 800 s/mm2; isometric voxel size of 1.5 mm, in-plan field of view of 160 × 160 mm, and acquisition matrix of 108 × 105).
Conventional morphological MR images included T2-weighted (T2W) turbo spin-echo sequences in transverse, dorsal, and sagittal planes, a transverse fluid-attenuated inversion recovery (FLAIR), a transverse T2* or a susceptibility-weighted sequence, and a 3D T1W gradient echo sequence.
In the dogs with idiopathic epilepsy, the 3D T1W sequence was repeated after intravenous injection of contrast media [Gadodiamide (Omniscan) GE HealthcareAG, Glattbrugg, Switzerland, or Gadoteric-acid (Dotarem), Guerbet AG, Zürich, Switzerland].
The echo-planar DTI sequence was performed in a transverse plane (TR 8,191 ms; TE 81 ms) with 32 diffusion directions (single low b value = 0 s/mm2; maximal b value = 800 s/mm2; isometric voxel size of 1.5 mm, in-plan field of view of 160 × 160 mm, and acquisition matrix of 108 × 105).
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