Vagus Nerve Stimulation in Rats

All subjects underwent headcap and VNS cuff implantations, as previously described [3 (link)–5 , 7 (link), 12 (link)]. Immediately following lesion surgery, a two channel connector was attached with acrylic to four skull screws. An incision and blunt dissection of the neck exposed the left cervical vagus nerve. Stimulation of the left branch of the vagus avoids cardiac complications [4 (link), 5 , 7 (link)]. The nerve was placed inside the cuff (5-6 kΩ impedance), and cuff leads were tunneled subcutaneously and attached to the two-channel connector atop the skull. Rats were provided amoxicillin (5 mg) and carprofen (1 mg) for three days following surgery.

Partial Protocol Preview
This section provides a glimpse into the protocol.
The remaining content is hidden due to licensing restrictions, but the full text is available at the following link: Access Free Full Text.

Hays S.A., Khodaparast N., Ruiz A., Sloan A.M., Hulsey D.R., Rennaker RL I.I, & Kilgard M.P. (2014). The timing and amount of vagus nerve stimulation during rehabilitative training affect post-stroke recovery of forelimb strength. Neuroreport, 25(9), 682-688.

Publication 2014

Amoxicillin Cardiac Carprofen Cervical Dissection neck Implantations Nerve Rats Skull Surgery Vagus nerve Vagus stimulation

Corresponding Organization :

Other organizations : The University of Texas at Dallas, Institut des Sciences Cognitives Marc Jeannerod

Top 5 similar protocols

Protocol cited in 6 other protocols

Variable analysis

independent variables

Stimulation of the left branch of the vagus nerve

dependent variables

Cardiac complications

control variables

Headcap and VNS cuff implantations
Rats provided amoxicillin (5 mg) and carprofen (1 mg) for three days following surgery

Annotations

Based on most similar protocols

Etiam vel ipsum. Morbi facilisis vestibulum nisl. Praesent cursus laoreet felis. Integer adipiscing pretium orci. Nulla facilisi. Quisque posuere bibendum purus. Nulla quam mauris, cursus eget, convallis ac, molestie non, enim. Aliquam congue. Quisque sagittis nonummy sapien. Proin molestie sem vitae urna. Maecenas lorem.

As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!