We searched databases including Medline, Embase, Cochrane Library and Web of Science for articles by the end of 30 September 2022. Publications in any language were considered. We used the following items as keywords: (‘angiotensin converting enzyme inhibitor’ OR ‘angiotensin receptor blocker’ OR ‘renin angiotensin system’) AND (‘chronic obstructive pulmonary disease’ OR ‘COPD’ OR ‘chronic obstructive lung disease’, ‘emphysema’). Please see the details in online supplemental material 1 .
Protocol detail
RAAS Inhibitors and COPD Outcomes
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Angiotensin converting enzyme inhibitor
Angiotensin receptor blocker
Chronic obstructive lung disease
Emphysema
Library
Renin angiotensin system
Corresponding Organization : Xuzhou Medical College
Other organizations : Jiangsu Vocational College of Medicine, Shanghai University of Traditional Chinese Medicine, Shuguang Hospital
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Variable analysis
independent variables
- Angiotensin converting enzyme inhibitor
- Angiotensin receptor blocker
- Renin angiotensin system
- Chronic obstructive pulmonary disease
- Chronic obstructive lung disease
- Emphysema
- Control variables not explicitly mentioned
- Positive and negative controls not explicitly mentioned
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