Optimized Diffusion Imaging for Tractography

These are the protocols recommended for tractography on the FMRIB-center 3 T Siemens Verio scanner. All scanning was performed using monopolar Stejskal–Tanner (ST) diffusion weighting, a single shell with a b-value of 1500 s/mm², 60 distinct diffusion gradients optimized on a half sphere and then re-distributed on the whole sphere and four b = 0 images interspersed. The total of 64 scans were repeated twice with opposing phase-encode directions (A→P and P→A) and using GRAPPA with an in-plane acceleration of 2. No multi-band (across plane acceleration) was used.

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Andersson J.L, & Sotiropoulos S.N. (2016). An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging. Neuroimage, 125, 1063-1078.

Publication 2016

Acceleration Diffusion Scans

Corresponding Organization :

Other organizations : Wellcome Centre for Integrative Neuroimaging

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Protocol cited in 504 other protocols

Variable analysis

independent variables

Diffusion weighting: Monopolar Stejskal–Tanner (ST) diffusion weighting
B-value: 1500 s/mm^2
Number of diffusion gradients: 60 distinct diffusion gradients optimized on a half sphere and then re-distributed on the whole sphere
Number of b=0 images: Four
Repetition of scans: Two with opposing phase-encode directions (A->P and P->A)
GRAPPA acceleration: In-plane acceleration of 2
Multi-band (across plane acceleration): Not used

dependent variables

Outcomes from tractography (not explicitly specified)

control variables

Scanner: FMRIB-center 3 T Siemens Verio
Diffusion weighting: Monopolar Stejskal–Tanner (ST) diffusion weighting

Annotations

Based on most similar protocols

Use monopolar Stejskal–Tanner (ST) diffusion weighting, a single shell with a b-value of 1500 s/mm^2, 60 distinct diffusion gradients optimized on a half sphere and then re-distributed on the whole sphere and four b = 0 images interspersed. (Input protocol)

Repeat the total of 64 scans twice with opposing phase-encode directions (A→P and P→A) and using GRAPPA with an in-plane acceleration of 2. (Input protocol)

Use a diffusion spin-echo single shot echo planar imaging sequence with 64 diffusion directions (effective b-value of 1,000 s/mm^2), eight images with no diffusion weight in the anterior–posterior phase encoding direction and eight images with no diffusion weight in the reverse phase encoding direction. (Protocol 1)

Validate obtained tracts using the LiFE software, which predicts the diffusion signal using the orientation of the fascicles present in obtained connections and compares it to the acquired MR data. Fascicles with zero-weights are discarded from the analysis. (Protocol 2)

Acquire diffusion-weighted data using a 3D-segmented echo planar imaging sequence with 54 directions (b = 4500 s/mm^2) and six b = 0 images. Acquire structural data using a 3D balanced steady-state-free precession sequence. (Protocol 3)

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